Juvenile xanthogranuloma - Xanthogranuloma Dhallinta
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ReferencesJuvenile xanthogranuloma (JXG) waa xaalad maqaarka oo dhif ah waana nooca ugu badan ee non‑Langerhans cell histiocytosis ee carruurta. Qiyaastii 75 % ee kiisaska, nabarradani waxay soo baxaan sanadka ugu horreeya ee nolosha, iyo in ka badan 15‑20 % bukaannada ayaa leh nabaro laga bilaabo dhalashada. Iyadoo ay naadir ku tahay dadka waaweyn, JXG waxay caadi ahaan ku dhacdaa dadka da'doodu u dhaxayso labaatan ilaa soddon sano, waxaana badi bukaannada qaangaarka ah ay leeyihiin hal nabar. Kiliinik ahaan, waxay u muuqataa sida hal ama dhowr buro adag oo jaale‑orange‑brown ah, inta badan wejiga, qoorta, iyo jirka sare. Nabarada afka waa wax aan caadi ahayn laakiin waxay u muuqan karaan sida buro jaale ah oo ku taal dhinacyada carrabka ama meel kale oo afka ah, sida gingiva, xuubka afka, ama xagga sare ee afka, waxaana suurtogal ah inay boogaan oo dhiig baxaan. Nabarada maqaarku badanaa waa asymptomatic waxayna u muuqdaan inay si iskeed ah u baaba'aan dhowr sano. In kasta oo ay naadir tahay, ka‑qaybgalka indhaha waa goobta ugu badan ee ka baxsan maqaarka, oo ay ku xigto ka‑qaybgalka sanbabada. Ocular JXG caadi ahaan waxay saamaysaa hal indho oo keliya waxayna ku dhacdaa in ka yar 0.5 % bukaannada, in kasta oo qiyaastii 40 % ka mid ah kuwa ay indhahoodu ku lug leeyihiin ay sidoo kale leeyihiin nabaro badan oo maqaarka ah marka la ogaado.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranulomas (JXGs) waa cudurro aan caadi ahayn oo qayb ka ah qaybta weyn ee non‑Langerhans cell histiocytosis. Waxay caadi ahaan u muuqdaan hal ama in ka badan oo macules ama papules cas‑huruud ah (macules, papules), oo inta badan laga helo wajiga ama qoorta. JXG‑yadu badankoodu waxay koraan marka ay dhashaan ama sannadka ugu horreeya ee nolosha. In kasta oo ay tahay wax aan caadi ahayn, mararka qaarkood waxay saameyn karaan meelaha ka baxsan maqaarka, iyada oo ku lug lahaanshaha indhaha (ocular involvement) ay tahay wax la daawado sida ku cad suugaanta jirta. Guud ahaan, JXG‑yadu maqaarka iskood bay u baaba'aan oo caadi ahaan uma baahna daaweyn.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Dhaawaca indhaha waxa uu ka muuqdaa ilaa 10 % dadka qaba JXG wuxuuna saameyn karaa aragtidooda. In kasta oo nabarrada maqaarku ay caadi ahaan iskood u baaba'aan, nabarrada indhaha si dhif ah ayay iskood u baaba'aan, waxayna inta badan u baahan yihiin daaweyn.